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Improved resolution of single channel dwell times reveals mechanisms of binding, priming, and gating in muscle AChR

The acetylcholine receptor (AChR) from vertebrate skeletal muscle initiates voluntary movement, and its kinetics of activation are crucial for maintaining the safety margin for neuromuscular transmission. Furthermore, the kinetic mechanism of the muscle AChR serves as an archetype for understanding...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Mukhtasimova, Nuriya, daCosta, Corrie J.B., Sine, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924934/
https://ncbi.nlm.nih.gov/pubmed/27353445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611584
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