Loading...

Congenital myasthenia–related AChR δ subunit mutation interferes with intersubunit communication essential for channel gating

Congenital myasthenias (CMs) arise from defects in neuromuscular junction–associated proteins. Deciphering the molecular bases of the CMs is required for therapy and illuminates structure-function relationships in these proteins. Here, we analyze the effects of a mutation in 1 of 4 homologous subuni...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Shen, Xin-Ming, Fukuda, Taku, Ohno, Kinji, Sine, Steven M., Engel, Andrew G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289798/
https://ncbi.nlm.nih.gov/pubmed/18398509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34527
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!