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Improved resolution of single channel dwell times reveals mechanisms of binding, priming, and gating in muscle AChR

The acetylcholine receptor (AChR) from vertebrate skeletal muscle initiates voluntary movement, and its kinetics of activation are crucial for maintaining the safety margin for neuromuscular transmission. Furthermore, the kinetic mechanism of the muscle AChR serves as an archetype for understanding...

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Detalles Bibliográficos
Publicado en:J Gen Physiol
Autores principales: Mukhtasimova, Nuriya, daCosta, Corrie J.B., Sine, Steven M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924934/
https://ncbi.nlm.nih.gov/pubmed/27353445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611584
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