Učitavanje...

Stoichiometry for α-bungarotoxin block of α7 acetylcholine receptors

α-Bungarotoxin (α-Btx) binds to the five agonist binding sites on the homopentameric α7-acetylcholine receptor, yet the number of bound α-Btx molecules required to prevent agonist-induced channel opening remains unknown. To determine the stoichiometry for α-Btx blockade, we generate receptors compri...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: daCosta, Corrie J. B., Free, Chris R., Sine, Steven M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544739/
https://ncbi.nlm.nih.gov/pubmed/26282895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9057
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!