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α4β2 Nicotinic Acetylcholine Receptors: RELATIONSHIPS BETWEEN SUBUNIT STOICHIOMETRY AND FUNCTION AT THE SINGLE CHANNEL LEVEL

Acetylcholine receptors comprising α4 and β2 subunits are the most abundant class of nicotinic acetylcholine receptor in the brain. They contribute to cognition, reward, mood, and nociception and are implicated in a range of neurological disorders. Previous measurements of whole-cell macroscopic cur...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mazzaferro, Simone, Bermudez, Isabel, Sine, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314170/
https://ncbi.nlm.nih.gov/pubmed/28031459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.764183
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