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α4β2 Nicotinic Acetylcholine Receptors: RELATIONSHIPS BETWEEN SUBUNIT STOICHIOMETRY AND FUNCTION AT THE SINGLE CHANNEL LEVEL

Acetylcholine receptors comprising α4 and β2 subunits are the most abundant class of nicotinic acetylcholine receptor in the brain. They contribute to cognition, reward, mood, and nociception and are implicated in a range of neurological disorders. Previous measurements of whole-cell macroscopic cur...

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Pubblicato in:J Biol Chem
Autori principali: Mazzaferro, Simone, Bermudez, Isabel, Sine, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314170/
https://ncbi.nlm.nih.gov/pubmed/28031459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.764183
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