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Potentiation of a neuronal nicotinic receptor via pseudo-agonist site
Neuronal nicotinic receptors containing α4 and β2 subunits assemble in two pentameric stoichiometries, (α4)(3)(β2)(2) and (α4)(2)(β2)(3), each with distinct pharmacological signatures; (α4)(3)(β2)(2) receptors are strongly potentiated by the drug NS9283, whereas (α4)(2)(β2)(3) receptors are unaffect...
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| Publicado no: | Cell Mol Life Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8022356/ https://ncbi.nlm.nih.gov/pubmed/30600358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2993-7 |
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