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Non-equivalent Ligand Selectivity of Agonist Sites in (α4β2)(2)α4 Nicotinic Acetylcholine Receptors: A KEY DETERMINANT OF AGONIST EFFICACY
The α4β2 nicotinic acetylcholine receptor (nAChR) is the most abundant nAChR type in the brain, and this receptor type exists in alternate (α4β2)(2)α4 and (α4β2)(2)β2 forms, which are activated by agonists with strikingly differing efficacies. Recent breakthroughs have identified an additional opera...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118137/ https://ncbi.nlm.nih.gov/pubmed/24936069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555136 |
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