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The fifth subunit of the (α4β2)(2)β2 nicotinic ACh receptor modulates maximal ACh responses

BACKGROUND AND PURPOSE: The fifth subunit in the (α4β2)(2)α4 nicotinic ACh receptor (nAChR) plays a determining role in the pharmacology of this nAChR type. Here, we have examined the role of the fifth subunit in the ACh responses of the (α4β2)(2)β2 nAChR type. EXPERIMENTAL APPROACH: The role of the...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: New, Karina, Del Villar, Silvia Garcia, Mazzaferro, Simone, Alcaino, Constanza, Bermudez, Isabel
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5978951/
https://ncbi.nlm.nih.gov/pubmed/28600847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13905
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