DNA methylation of indoleamine 2,3-dioxygenase 1 (IDO1) in head and neck squamous cell carcinomas correlates with IDO1 expression, HPV status, patients’ survival, immune cell infiltrates, mutational load, and interferon γ signature

BACKGROUND: The immune checkpoint, indoleamine 2,3-dioxygenase 1, is under investigation as target of novel immunotherapies for cancers, including head and neck squamous cell carcinomas (HNSCC). The aim of our study was to analyze DNA methylation of the encoding gene (IDO1) in HNSCC. METHODS: Methyl...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:EBioMedicine
Autores principales: Sailer, Verena, Sailer, Ulrike, Bawden, Emma Grace, Zarbl, Romina, Wiek, Constanze, Vogt, Timo J., Dietrich, Joern, Loick, Sophia, Grünwald, Ingela, Toma, Marieta, Golletz, Carsten, Gerstner, Andreas, Kristiansen, Glen, Bootz, Friedrich, Scheckenbach, Kathrin, Landsberg, Jennifer, Dietrich, Dimo
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838413/
https://ncbi.nlm.nih.gov/pubmed/31628024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.038
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares