Molecular and immune correlates of TIM-3 (HAVCR2) and galectin 9 (LGALS9) mRNA expression and DNA methylation in melanoma

BACKGROUND: The T cell immunoglobulin and mucin-domain containing-3 receptor TIM-3 (also known as hepatitis A virus cellular receptor 2, encoded by HAVCR2) and its ligand galectin 9 (LGALS9) are promising targets for immune checkpoint inhibition immunotherapies. However, little is known about epigen...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Holderried, Tobias A. W., de Vos, Luka, Bawden, Emma Grace, Vogt, Timo J., Dietrich, Joern, Zarbl, Romina, Bootz, Friedrich, Kristiansen, Glen, Brossart, Peter, Landsberg, Jennifer, Dietrich, Dimo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868848/
https://ncbi.nlm.nih.gov/pubmed/31747929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0752-8
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