Clinical performance validation of PITX2 DNA methylation as prognostic biomarker in patients with head and neck squamous cell carcinoma

BACKGROUND: Despite advances in combined modality therapy, outcomes in head and neck squamous cell cancer (HNSCC) remain dismal with five-year overall survival rates of less than 50%. Prognostic biomarkers are urgently needed to identify patients with a high risk of death after initial curative trea...

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Vydáno v:PLoS One
Hlavní autoři: Sailer, Verena, Gevensleben, Heidrun, Dietrich, Joern, Goltz, Diane, Kristiansen, Glen, Bootz, Friedrich, Dietrich, Dimo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472307/
https://ncbi.nlm.nih.gov/pubmed/28617833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179412
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