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Chemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals

Strategies for the direct chemical activation of specific signaling proteins could provide powerful tools for interrogating cellular signal transduction. However, targeted protein activation is chemically challenging, and few broadly applicable activation strategies for signaling enzymes have been d...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Plaman, Bailey A., Chan, Wai Cheung, Bishop, Anthony C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834593/
https://ncbi.nlm.nih.gov/pubmed/31695052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52002-1
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