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Probing the target-specific inhibition of sensitized protein tyrosine phosphatases with biarsenical probes
Selective control of enzyme activity is critical for elucidating the roles of specific proteins in signaling pathways. One potential means for developing truly target-specific inhibitors involves the use of protein engineering to sensitize a target enzyme to inhibition by a small molecule that does...
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| Publicado no: | Org Biomol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303503/ https://ncbi.nlm.nih.gov/pubmed/25460004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob02256d |
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