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Chemical rescue of protein tyrosine phosphatase activity
We report that the activity of a rationally engineered protein tyrosine phosphatase (PTP) mutant can be fully rescued by the addition of the biarsenical fluorescein derivative FlAsH, a compound that does not affect the activity of wild-type PTPs.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834275/ https://ncbi.nlm.nih.gov/pubmed/20062887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b919815f |
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