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Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity
Rhesus cytomegalovirus (RhCMV)-based vaccines maintain effector-memory T cell responses (T(EM)) that protect ~50% of rhesus monkeys (RMs) challenged with simian immunodeficiency virus (SIV). Because human CMV (HCMV) causes disease in immune-deficient subjects, clinical translation will depend upon a...
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| Veröffentlicht in: | Sci Transl Med |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6830438/ https://ncbi.nlm.nih.gov/pubmed/31316006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw2603 |
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