Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus

The natural killer cell receptor NKG2D activates NK cells by engaging one of several ligands (NKG2DLs) belonging to either the MIC or ULBP families. Human cytomegalovirus (HCMV) UL16 and UL142 counteract this activation by retaining NKG2DLs and US18 and US20 act via lysomal degradation but the impor...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Sturgill, Elizabeth R., Malouli, Daniel, Hansen, Scott G., Burwitz, Benjamin J., Seo, Seongkyung, Schneider, Christine L., Womack, Jennie L., Verweij, Marieke C., Ventura, Abigail B., Bhusari, Amruta, Jeffries, Krystal M., Legasse, Alfred W., Axthelm, Michael K., Hudson, Amy W., Sacha, Jonah B., Picker, Louis J., Früh, Klaus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006984/
https://ncbi.nlm.nih.gov/pubmed/27580123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005868
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