Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus

The natural killer cell receptor NKG2D activates NK cells by engaging one of several ligands (NKG2DLs) belonging to either the MIC or ULBP families. Human cytomegalovirus (HCMV) UL16 and UL142 counteract this activation by retaining NKG2DLs and US18 and US20 act via lysomal degradation but the impor...

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Vydáno v:PLoS Pathog
Hlavní autoři: Sturgill, Elizabeth R., Malouli, Daniel, Hansen, Scott G., Burwitz, Benjamin J., Seo, Seongkyung, Schneider, Christine L., Womack, Jennie L., Verweij, Marieke C., Ventura, Abigail B., Bhusari, Amruta, Jeffries, Krystal M., Legasse, Alfred W., Axthelm, Michael K., Hudson, Amy W., Sacha, Jonah B., Picker, Louis J., Früh, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006984/
https://ncbi.nlm.nih.gov/pubmed/27580123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005868
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