Cytomegalovirus pp65 limits dissemination but is dispensable for persistence

The most abundantly produced virion protein in human cytomegalovirus (HCMV) is the immunodominant phosphoprotein 65 (pp65), which is frequently included in CMV vaccines. Although it is nonessential for in vitro CMV growth, pp65 displays immunomodulatory functions that support a potential role in pri...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Malouli, Daniel, Hansen, Scott G., Nakayasu, Ernesto S., Marshall, Emily E., Hughes, Colette M., Ventura, Abigail B., Gilbride, Roxanne M., Lewis, Matthew S., Xu, Guangwu, Kreklywich, Craig, Whizin, Nathan, Fischer, Miranda, Legasse, Alfred W., Viswanathan, Kasinath, Siess, Don, Camp, David G., Axthelm, Michael K., Kahl, Christoph, DeFilippis, Victor R., Smith, Richard D., Streblow, Daniel N., Picker, Louis J., Früh, Klaus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002596/
https://ncbi.nlm.nih.gov/pubmed/24691437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67420
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