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Sensitive Oligodeoxynucleotide Synthesis Using Dim and Dmoc as Protecting Groups

In traditional oligodeoxynucleotide (ODN) synthesis, phosphate groups are protected with 2-cyanoethyl group, and amino groups are protected with acyl groups. At the end of ODN synthesis, deprotection is achieved with strong bases and nucleophiles. Therefore, traditional technologies are not suitable...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Org Chem
Prif Awduron: Shahsavari, Shahien, Eriyagama, Dhananjani N. A. M., Chen, Jinsen, Halami, Bhaskar, Yin, Yipeng, Chillar, Komal, Fang, Shiyue
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825528/
https://ncbi.nlm.nih.gov/pubmed/31536351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b01527
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