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Incorporation of Sensitive Ester and Chloropurine Groups into Oligodeoxynucleotides through Solid Phase Synthesis

Nucleosides containing ester groups that are sensitive to nucleophiles were incorporated into oligodeoxynucleotides (ODNs) through solid phase chemical synthesis. The sensitive esters are located on a purine nucleobase. They are the esters of ethyl, 2-methoxyethyl, 4-methoxyphenyl and phenyl groups,...

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Publicado en:ChemistrySelect
Autores principales: Halami, Bhaskar, Shahsavari, Shahien, Nelson, Zack, Prehoda, Lucas, Eriyagama, Dhananjani Nisansala Adikari Mudiyanselage, Fang, Shiyue
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420219/
https://ncbi.nlm.nih.gov/pubmed/30886889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/slct.201801484
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