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Incorporation of Sensitive Ester and Chloropurine Groups into Oligodeoxynucleotides through Solid Phase Synthesis

Nucleosides containing ester groups that are sensitive to nucleophiles were incorporated into oligodeoxynucleotides (ODNs) through solid phase chemical synthesis. The sensitive esters are located on a purine nucleobase. They are the esters of ethyl, 2-methoxyethyl, 4-methoxyphenyl and phenyl groups,...

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Publicat a:ChemistrySelect
Autors principals: Halami, Bhaskar, Shahsavari, Shahien, Nelson, Zack, Prehoda, Lucas, Eriyagama, Dhananjani Nisansala Adikari Mudiyanselage, Fang, Shiyue
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420219/
https://ncbi.nlm.nih.gov/pubmed/30886889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/slct.201801484
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