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Incorporation of Sensitive Ester and Chloropurine Groups into Oligodeoxynucleotides through Solid Phase Synthesis

Nucleosides containing ester groups that are sensitive to nucleophiles were incorporated into oligodeoxynucleotides (ODNs) through solid phase chemical synthesis. The sensitive esters are located on a purine nucleobase. They are the esters of ethyl, 2-methoxyethyl, 4-methoxyphenyl and phenyl groups,...

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Detalhes bibliográficos
Publicado no:ChemistrySelect
Main Authors: Halami, Bhaskar, Shahsavari, Shahien, Nelson, Zack, Prehoda, Lucas, Eriyagama, Dhananjani Nisansala Adikari Mudiyanselage, Fang, Shiyue
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420219/
https://ncbi.nlm.nih.gov/pubmed/30886889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/slct.201801484
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