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Electrophilic oligodeoxynucleotide synthesis using dM-Dmoc for amino protection
Solid-phase synthesis of electrophilic oligodeoxynucleotides (ODNs) was achieved using dimethyl-Dmoc (dM-Dmoc) as amino protecting group. Due to the high steric hindrance of the 2-(propan-2-ylidene)-1,3-dithiane side product from deprotection, the use of excess nucleophilic scavengers such as anilin...
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| Publicado no: | Beilstein J Org Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541367/ https://ncbi.nlm.nih.gov/pubmed/31164948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.108 |
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