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Sensitive Oligodeoxynucleotide Synthesis Using Dim and Dmoc as Protecting Groups
In traditional oligodeoxynucleotide (ODN) synthesis, phosphate groups are protected with 2-cyanoethyl group, and amino groups are protected with acyl groups. At the end of ODN synthesis, deprotection is achieved with strong bases and nucleophiles. Therefore, traditional technologies are not suitable...
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| Publicado no: | J Org Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6825528/ https://ncbi.nlm.nih.gov/pubmed/31536351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b01527 |
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