Synthesis of Oligodeoxynucleotides Containing Electrophilic Groups

Using 1,3-dithian-2-yl-methoxycarbonyl (Dmoc) as protecting groups and linker for oligodeoxynucleotide (ODN) synthesis, deprotection and cleavage are achieved under non-nucleophilic oxidative conditions. The nucleophile-sensitive thioester and α-chloroacetyl groups are conveniently incorporated into...

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Bibliographic Details
Published in:	Org Lett
Main Authors:	Lin, Xi, Chen, Jinsen, Shahsavari, Shahien, Green, Nathanael, Goyal, Deepti, Fang, Shiyue
Format:	Artigo
Language:	Inglês
Published:	2016
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4975647/ https://ncbi.nlm.nih.gov/pubmed/27447361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b01878
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Synthesis of Oligodeoxynucleotides Containing Electrophilic Groups

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