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Synthesis of Oligodeoxynucleotides Containing Electrophilic Groups
Using 1,3-dithian-2-yl-methoxycarbonyl (Dmoc) as protecting groups and linker for oligodeoxynucleotide (ODN) synthesis, deprotection and cleavage are achieved under non-nucleophilic oxidative conditions. The nucleophile-sensitive thioester and α-chloroacetyl groups are conveniently incorporated into...
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| Veröffentlicht in: | Org Lett |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975647/ https://ncbi.nlm.nih.gov/pubmed/27447361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b01878 |
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