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Synthesis of Oligodeoxynucleotides Containing Electrophilic Groups

Using 1,3-dithian-2-yl-methoxycarbonyl (Dmoc) as protecting groups and linker for oligodeoxynucleotide (ODN) synthesis, deprotection and cleavage are achieved under non-nucleophilic oxidative conditions. The nucleophile-sensitive thioester and α-chloroacetyl groups are conveniently incorporated into...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Lin, Xi, Chen, Jinsen, Shahsavari, Shahien, Green, Nathanael, Goyal, Deepti, Fang, Shiyue
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975647/
https://ncbi.nlm.nih.gov/pubmed/27447361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b01878
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