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Therapeutic role of a cysteine precursor, OTC, in ischemic stroke is mediated by improved proteostasis in mice
Oxidative stress aggravates brain injury following ischemia/reperfusion (I/R). We previously showed that ubiquilin-1 (Ubqln1), a ubiquitin-like protein, improves proteostasis and protects brains against oxidative stress and I/R induced brain injury. Here, we demonstrate that a small molecule compoun...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Transl Stroke Res |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6824933/ https://ncbi.nlm.nih.gov/pubmed/31049841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-019-00707-w |
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