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Therapeutic role of a cysteine precursor, OTC, in ischemic stroke is mediated by improved proteostasis in mice
Oxidative stress aggravates brain injury following ischemia/reperfusion (I/R). We previously showed that ubiquilin-1 (Ubqln1), a ubiquitin-like protein, improves proteostasis and protects brains against oxidative stress and I/R induced brain injury. Here, we demonstrate that a small molecule compoun...
שמור ב:
| הוצא לאור ב: | Transl Stroke Res |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6824933/ https://ncbi.nlm.nih.gov/pubmed/31049841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-019-00707-w |
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