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Peripherally misfolded proteins exacerbate ischemic stroke-induced neuroinflammation and brain injury

BACKGROUND: Protein aggregates can be found in peripheral organs, such as the heart, kidney, and pancreas, but little is known about the impact of peripherally misfolded proteins on neuroinflammation and brain functional recovery following ischemic stroke. METHODS: Here, we studied the ischemia/repe...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Liu, Yanying, Subedi, Kalpana, Baride, Aravind, Romanova, Svetlana, Callegari, Eduardo, Huber, Christa C., Wang, Xuejun, Wang, Hongmin
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818745/
https://ncbi.nlm.nih.gov/pubmed/33472658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02081-7
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