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Attenuation of ischemic stroke-caused brain injury by a monoamine oxidase inhibitor involves improved proteostasis and reduced neuroinflammation

Mitochondrial dysfunction and oxidative stress play a key role in ischemia/reperfusion (I/R) induced brain injury. We previously showed that ubiquilin-1 (Ubqln1), a ubiquitin-like protein, improves proteostasis and protects brains against oxidative stress and I/R induced brain injury. We demonstrate...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Liu, Yanying, Feng, Shelley, Subedi, Kalpana, Wang, Hongmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035161/
https://ncbi.nlm.nih.gov/pubmed/31620993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01788-2
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