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Enhanced proteostasis in post-ischemic stroke mouse brains by ubiquilin-1 promotes functional recovery

Stroke is pathologically associated with oxidative stress, protein damage, and neuronal loss. We previously reported that overexpression of a ubiquitin-like protein, ubiquilin-1 (Ubqln), protects neurons against ischemia-caused brain injury, while knockout of the gene exacerbates cerebral ischemia-c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Mol Neurobiol
Main Authors: Liu, Yanying, Qiao, Fangfang, Wang, Hongmin
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462886/
https://ncbi.nlm.nih.gov/pubmed/27928652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-016-0451-3
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