Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors

A limiting factor for the use of adeno-associated viruses (AAVs) as vectors in gene therapy is the broad tropism of AAV serotypes, i.e., the parallel infection of several cell types. Nanobodies are single immunoglobulin variable domains from heavy chain antibodies that naturally occur in camelids. T...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Eichhoff, Anna Marei, Börner, Kathleen, Albrecht, Birte, Schäfer, Waldemar, Baum, Natalie, Haag, Friedrich, Körbelin, Jakob, Trepel, Martin, Braren, Ingke, Grimm, Dirk, Adriouch, Sahil, Koch-Nolte, Friedrich
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819893/
https://ncbi.nlm.nih.gov/pubmed/31687421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.09.003
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker