Engineering and Evolution of Synthetic Adeno-Associated Virus (AAV) Gene Therapy Vectors via DNA Family Shuffling

Por Kienle, Eike, Senís, Elena, Börner, Kathleen, Niopek, Dominik, Wiedtke, Ellen, Grosse, Stefanie, Grimm, Dirk
Publicado em 2012

Type I Interferon Regulates the Expression of Long Non-Coding RNAs

Por Carnero, Elena, Barriocanal, Marina, Segura, Victor, Guruceaga, Elizabeth, Prior, Celia, Börner, Kathleen, Grimm, Dirk, Fortes, Puri
Publicado no Front Immunol (2014)

Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver

Por Grimm, Dirk, Wang, Lora, Lee, Joyce S., Schürmann, Nina, Gu, Shuo, Börner, Kathleen, Storm, Theresa A., Kay, Mark A.
Publicado em 2010

T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes

Por Mueller, Stephanie, Huard, Jérémy, Waldow, Katharina, Huang, Xiaoyun, D'Alessandro, Lorenza A, Bohl, Sebastian, Börner, Kathleen, Grimm, Dirk, Klamt, Steffen, Klingmüller, Ursula, Schilling, Marcel
Publicado no Mol Syst Biol (2015)

Relevance of Assembly-Activating Protein for Adeno-associated Virus Vector Production and Capsid Protein Stability in Mammalian and Insect Cells

Por Grosse, Stefanie, Penaud-Budloo, Magalie, Herrmann, Anne-Kathrin, Börner, Kathleen, Fakhiri, Julia, Laketa, Vibor, Krämer, Chiara, Wiedtke, Ellen, Gunkel, Manuel, Ménard, Lucie, Ayuso, Eduard, Grimm, Dirk
Publicado no J Virol (2017)

Low-level shRNA Cytotoxicity Can Contribute to MYC-induced Hepatocellular Carcinoma in Adult Mice

Por Beer, Shelly, Bellovin, David I, Lee, Joyce S, Komatsubara, Kimberly, Wang, Lora S, Koh, Huishan, Börner, Kathleen, Storm, Theresa A, Davis, Corrine R, Kay, Mark A, Felsher, Dean W, Grimm, Dirk
Publicado em 2009

AAV8-Mediated In Vivo Overexpression of miR-155 Enhances the Protective Capacity of Genetically Attenuated Malarial Parasites

Por Hentzschel, Franziska, Hammerschmidt-Kamper, Christiane, Börner, Kathleen, Heiss, Kirsten, Knapp, Bettina, Sattler, Julia M, Kaderali, Lars, Castoldi, Mirco, Bindman, Julia G, Malato, Yann, Willenbring, Holger, Mueller, Ann-Kristin, Grimm, Dirk
Publicado no Mol Ther (2014)

Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines

Por Börner, Kathleen, Niopek, Dominik, Cotugno, Gabriella, Kaldenbach, Michaela, Pankert, Teresa, Willemsen, Joschka, Zhang, Xian, Schürmann, Nina, Mockenhaupt, Stefan, Serva, Andrius, Hiet, Marie-Sophie, Wiedtke, Ellen, Castoldi, Mirco, Starkuviene, Vytaute, Erfle, Holger, Gilbert, Daniel F., Bartenschlager, Ralf, Boutros, Michael, Binder, Marco, Streetz, Konrad, Kräusslich, Hans-Georg, Grimm, Dirk
Publicado em 2013