T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes

Liver regeneration is a tightly controlled process mainly achieved by proliferation of usually quiescent hepatocytes. The specific molecular mechanisms ensuring cell division only in response to proliferative signals such as hepatocyte growth factor (HGF) are not fully understood. Here, we combined...

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Publicat a:Mol Syst Biol
Autors principals: Mueller, Stephanie, Huard, Jérémy, Waldow, Katharina, Huang, Xiaoyun, D'Alessandro, Lorenza A, Bohl, Sebastian, Börner, Kathleen, Grimm, Dirk, Klamt, Steffen, Klingmüller, Ursula, Schilling, Marcel
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380929/
https://ncbi.nlm.nih.gov/pubmed/26148348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156032
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