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T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes

Liver regeneration is a tightly controlled process mainly achieved by proliferation of usually quiescent hepatocytes. The specific molecular mechanisms ensuring cell division only in response to proliferative signals such as hepatocyte growth factor (HGF) are not fully understood. Here, we combined...

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Bibliografski detalji
Izdano u:Mol Syst Biol
Glavni autori: Mueller, Stephanie, Huard, Jérémy, Waldow, Katharina, Huang, Xiaoyun, D'Alessandro, Lorenza A, Bohl, Sebastian, Börner, Kathleen, Grimm, Dirk, Klamt, Steffen, Klingmüller, Ursula, Schilling, Marcel
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380929/
https://ncbi.nlm.nih.gov/pubmed/26148348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156032
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