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Regulation of hepatic mitochondrial oxidation by glucose-alanine cycling during starvation in humans

In order to determine whether the glucose-alanine cycle regulates rates of hepatic mitochondrial oxidation in humans, we applied positional isotopomer NMR tracer analysis (PINTA) to assess rates of hepatic mitochondrial oxidation and pyruvate carboxylase flux in healthy volunteers following both an...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Petersen, Kitt Falk, Dufour, Sylvie, Cline, Gary W., Shulman, Gerald I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819088/
https://ncbi.nlm.nih.gov/pubmed/31545298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129913
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