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Regulation of hepatic mitochondrial oxidation by glucose-alanine cycling during starvation in humans

In order to determine whether the glucose-alanine cycle regulates rates of hepatic mitochondrial oxidation in humans, we applied positional isotopomer NMR tracer analysis (PINTA) to assess rates of hepatic mitochondrial oxidation and pyruvate carboxylase flux in healthy volunteers following both an...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Petersen, Kitt Falk, Dufour, Sylvie, Cline, Gary W., Shulman, Gerald I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819088/
https://ncbi.nlm.nih.gov/pubmed/31545298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129913
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