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Direct Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in Non Alcoholic Fatty Liver Disease by (13)C Magnetic Resonance Spectroscopy

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and there is great interest in understanding the potential role of alterations in mitochondrial metabolism in its pathogenesis. To address this question we assessed rates of hepatic mitochondrial oxidation in subjects...

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Détails bibliographiques
Publié dans:Cell Metab
Auteurs principaux: Petersen, Kitt Falk, Befroy, Douglas E., Dufour, Sylvie, Rothman, Douglas L., Shulman, Gerald I.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946568/
https://ncbi.nlm.nih.gov/pubmed/27411016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.06.005
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