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Direct Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in Non Alcoholic Fatty Liver Disease by (13)C Magnetic Resonance Spectroscopy

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and there is great interest in understanding the potential role of alterations in mitochondrial metabolism in its pathogenesis. To address this question we assessed rates of hepatic mitochondrial oxidation in subjects...

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Publicat a:Cell Metab
Autors principals: Petersen, Kitt Falk, Befroy, Douglas E., Dufour, Sylvie, Rothman, Douglas L., Shulman, Gerald I.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946568/
https://ncbi.nlm.nih.gov/pubmed/27411016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.06.005
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