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Direct Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in Non Alcoholic Fatty Liver Disease by (13)C Magnetic Resonance Spectroscopy

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and there is great interest in understanding the potential role of alterations in mitochondrial metabolism in its pathogenesis. To address this question we assessed rates of hepatic mitochondrial oxidation in subjects...

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Foilsithe in:Cell Metab
Main Authors: Petersen, Kitt Falk, Befroy, Douglas E., Dufour, Sylvie, Rothman, Douglas L., Shulman, Gerald I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946568/
https://ncbi.nlm.nih.gov/pubmed/27411016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.06.005
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