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Leptin mediates a glucose-fatty acid cycle to maintain glucose homeostasis in starvation

The transition from the fed to the fasted state necessitates a shift from carbohydrate to fat metabolism, which is thought to be mostly orchestrated by reductions in plasma insulin concentrations. Here we show in awake rats that insulinopenia per se does not cause this transition, but that both hypo...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Perry, Rachel J., Wang, Yongliang, Cline, Gary W., Rabin-Court, Aviva, Song, Joongyu D., Dufour, Sylvie, Zhang, Xian-Man, Petersen, Kitt Falk, Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766366/
https://ncbi.nlm.nih.gov/pubmed/29307489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.12.001
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