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Leptin mediates a glucose-fatty acid cycle to maintain glucose homeostasis in starvation

The transition from the fed to the fasted state necessitates a shift from carbohydrate to fat metabolism, which is thought to be mostly orchestrated by reductions in plasma insulin concentrations. Here we show in awake rats that insulinopenia per se does not cause this transition, but that both hypo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell
Päätekijät: Perry, Rachel J., Wang, Yongliang, Cline, Gary W., Rabin-Court, Aviva, Song, Joongyu D., Dufour, Sylvie, Zhang, Xian-Man, Petersen, Kitt Falk, Shulman, Gerald I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766366/
https://ncbi.nlm.nih.gov/pubmed/29307489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.12.001
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