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Pleotropic effects of leptin to reverse insulin resistance and diabetic ketoacidosis

In this review we discuss the mechanisms for the pleotropic effects of leptin replacement therapy to reverse liver and muscle insulin resistance in lipodystrophic individuals, as well as insulin-independent effects of leptin replacement therapy to suppress white adipose tissue lipolysis, hepatic glu...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Perry, Rachel J., Petersen, Kitt Falk, Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826798/
https://ncbi.nlm.nih.gov/pubmed/26961503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-3909-4
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