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Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system

Diabetes has become one of the major noninfectious diseases that seriously endanger public health. The formation of islet amyloid polypeptide (IAPP) affects the normal physiological functions of the body, such as glucose metabolism and lipid metabolism. The mature human IAPP protein (hIAPP) has a st...

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Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Zou, Xiaodong, Ouyang, Hongsheng, Yu, Tingting, Chen, Xue, Pang, Daxin, Tang, Xiaochun, Chen, Chengzhen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817862/
https://ncbi.nlm.nih.gov/pubmed/31659151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2056-5
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