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Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System

Genetically modified pigs are increasingly used for biomedical and agricultural applications. The efficient CRISPR/Cas9 gene editing system holds great promise for the generation of gene-targeting pigs without selection marker genes. In this study, we aimed to disrupt the porcine myostatin (MSTN) ge...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Kankan, Ouyang, Hongsheng, Xie, Zicong, Yao, Chaogang, Guo, Nannan, Li, Mengjing, Jiao, Huping, Pang, Daxin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643223/
https://ncbi.nlm.nih.gov/pubmed/26564781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16623
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