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Efficient Generation of Myostatin Gene Mutated Rabbit by CRISPR/Cas9
CRISPR/Cas9 has been widely used in generating site-specific genetically modified animal models. Myostatin (MSTN) is a negative regulator of muscle mass, related to muscle growth and differentiation. The knockout of MSTN with the desired phenotype of double muscle has been successfully generated in...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844959/ https://ncbi.nlm.nih.gov/pubmed/27113799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25029 |
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