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Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/Cas9 System

Paired-homeodomain transcription factor 4 (PAX4) gene encodes a transcription factor which plays an important role in the generation, differentiation, development, and survival of insulin-producing β-cells during mammalian pancreas development. PAX4 is a key diabetes mellitus (DM) susceptibility gen...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Xu, Yuanyuan, Wang, Yong, Song, Yuning, Deng, Jichao, Chen, Mao, Ouyang, Hongsheng, Lai, Liangxue, Li, Zhanjun
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071587/
https://ncbi.nlm.nih.gov/pubmed/29950431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.300448
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