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Generation and Phenotype Identification of PAX4 Gene Knockout Rabbit by CRISPR/Cas9 System
Paired-homeodomain transcription factor 4 (PAX4) gene encodes a transcription factor which plays an important role in the generation, differentiation, development, and survival of insulin-producing β-cells during mammalian pancreas development. PAX4 is a key diabetes mellitus (DM) susceptibility gen...
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| Publicado en: | G3 (Bethesda) |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Genetics Society of America
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071587/ https://ncbi.nlm.nih.gov/pubmed/29950431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.300448 |
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