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Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system

Diabetes has become one of the major noninfectious diseases that seriously endanger public health. The formation of islet amyloid polypeptide (IAPP) affects the normal physiological functions of the body, such as glucose metabolism and lipid metabolism. The mature human IAPP protein (hIAPP) has a st...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zou, Xiaodong, Ouyang, Hongsheng, Yu, Tingting, Chen, Xue, Pang, Daxin, Tang, Xiaochun, Chen, Chengzhen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817862/
https://ncbi.nlm.nih.gov/pubmed/31659151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2056-5
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