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Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system

Diabetes has become one of the major noninfectious diseases that seriously endanger public health. The formation of islet amyloid polypeptide (IAPP) affects the normal physiological functions of the body, such as glucose metabolism and lipid metabolism. The mature human IAPP protein (hIAPP) has a st...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Zou, Xiaodong, Ouyang, Hongsheng, Yu, Tingting, Chen, Xue, Pang, Daxin, Tang, Xiaochun, Chen, Chengzhen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817862/
https://ncbi.nlm.nih.gov/pubmed/31659151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2056-5
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