Esophageal 3D organoids of MPV17(-/-) mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition

Esophageal squamous cell carcinoma (ESCC) is an aggressive cancer with late-stage detection and poor prognosis. This emphasizes the need to identify new markers for early diagnosis and treatment. Altered mitochondrial genome (mtDNA) content in primary tumors correlates with poor patient prognosis. H...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Guha, Manti, Srinivasan, Satish, Sheehan, Maura M., Kijima, Takashi, Ruthel, Gordon, Whelan, Kelly, Tanaka, Koji, Klein-Szanto, Andres, Chandramouleeswaran, Prasanna M., Nakagawa, Hiroshi, Avadhani, Narayan G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2019
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817447/
https://ncbi.nlm.nih.gov/pubmed/31692873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27264
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